Risk of immune-mediated inflammatory diseases in newly diagnosed ankylosing spondylitis patients: a population-based matched cohort study
Identifieur interne : 000459 ( Main/Exploration ); précédent : 000458; suivant : 000460Risk of immune-mediated inflammatory diseases in newly diagnosed ankylosing spondylitis patients: a population-based matched cohort study
Auteurs : Hsin-Hua Chen [Taïwan] ; Wen-Cheng Chao [Taïwan] ; Yi-Hsing Chen [Taïwan] ; Tsu-Yi Hsieh [Taïwan] ; Kuo-Lung Lai [Taïwan] ; Yi-Ming Chen [Taïwan] ; Wei-Ting Hung [Taïwan] ; Ching-Tsai Lin [Taïwan] ; Chih-Wei Tseng [Taïwan] ; Ching-Heng Lin [Taïwan]Source :
- Arthritis Research & Therapy [ 1478-6354 ] ; 2019.
Abstract
To investigate the risk of immune-mediated inflammatory diseases (IMIDs) in patients with ankylosing spondylitis (AS).
Using 2003–2012 claims data from the Taiwanese National Health Insurance Research Database, we identified 30,911 newly diagnosed AS patients requiring medical therapy from 2006 to 2012. In addition, we randomly selected 309,110 non-AS individuals matching (1:10) the AS patients with regard to age, sex and the year of the index date. After excluding subjects with the corresponding prior IMIDs, we calculated the incidence rates (IRs) of various IMIDs in the AS and non-AS cohorts and estimated the hazard ratios (HRs) with 95% confidence intervals after adjusting for age, sex, the Charlson comorbidity index, the frequency of ambulatory visits during the follow-up period and medications. We conducted sensitivity analyses by excluding those who developed IMIDs within 3 months after the index date.
In the follow-up period, we found that newly diagnosed AS patients had significantly increased risks of acute anterior uveitis, psoriasis, Sjögren’s syndrome, thromboangiitis obliterans, Behcet’s disease and sarcoidosis. However, the risk of Sjögren’s syndrome did not increase in AS patients in the sensitivity analysis. In the same period, this study found no significant differences in the risks of Crohn’s disease, ulcerative colitis, systemic lupus erythematosus, systemic sclerosis, dermatomyositis, polymyositis, pemphigus and vitiligo between newly diagnosed AS patients and non-AS individuals. AS patients had a significantly reduced risk of rheumatoid arthritis.
Newly diagnosed Taiwanese AS patients had increased risks of acute anterior uveitis, psoriasis, thromboangiitis obliterans, Behcet’s disease and sarcoidosis, but a reduced risk of rheumatoid arthritis.
The online version of this article (10.1186/s13075-019-1980-1) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1186/s13075-019-1980-1
PubMed: 31464632
PubMed Central: 6716905
Affiliations:
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xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Yi Hsing" sort="Chen, Yi Hsing" uniqKey="Chen Y" first="Yi-Hsing" last="Chen">Yi-Hsing Chen</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0425 5914</institution-id><institution-id institution-id-type="GRID">grid.260770.4</institution-id><institution>School of Medicine,</institution><institution>National Yang-Ming University,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Hsieh, Tsu Yi" sort="Hsieh, Tsu Yi" uniqKey="Hsieh T" first="Tsu-Yi" last="Hsieh">Tsu-Yi Hsieh</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0425 5914</institution-id><institution-id institution-id-type="GRID">grid.260770.4</institution-id><institution>School of Medicine,</institution><institution>National Yang-Ming University,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff9"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Department of Medical Education,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff10"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2175 4846</institution-id><institution-id institution-id-type="GRID">grid.411298.7</institution-id><institution>Ph.D. Program of Business,</institution><institution>Feng Chia University,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation></author><author><name sortKey="Lai, Kuo Lung" sort="Lai, Kuo Lung" uniqKey="Lai K" first="Kuo-Lung" last="Lai">Kuo-Lung Lai</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff11"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0546 0241</institution-id><institution-id institution-id-type="GRID">grid.19188.39</institution-id><institution>Graduate Institute of Biomedical Electronics and Bioinformatics,</institution><institution>National Taiwan University,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Department of Medical Research,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0425 5914</institution-id><institution-id institution-id-type="GRID">grid.260770.4</institution-id><institution>School of Medicine,</institution><institution>National Yang-Ming University,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0532 3749</institution-id><institution-id institution-id-type="GRID">grid.260542.7</institution-id><institution>Institute of Biomedical Science and Rong-Hsing Research Center for Translational Medicine,</institution><institution>Chung-Hsing University,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff5"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0425 5914</institution-id><institution-id institution-id-type="GRID">grid.260770.4</institution-id><institution>Institute of Public Health and Community Medicine Research Center,</institution><institution>National Yang-Ming University,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation></author><author><name sortKey="Hung, Wei Ting" sort="Hung, Wei Ting" uniqKey="Hung W" first="Wei-Ting" last="Hung">Wei-Ting Hung</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff8"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1770 3722</institution-id><institution-id institution-id-type="GRID">grid.411432.1</institution-id><institution>Department of Nursing, College of Medicine & Nursing,</institution><institution>Hung Kuang University,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Ching Tsai" sort="Lin, Ching Tsai" uniqKey="Lin C" first="Ching-Tsai" last="Lin">Ching-Tsai Lin</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation></author><author><name sortKey="Tseng, Chih Wei" sort="Tseng, Chih Wei" uniqKey="Tseng C" first="Chih-Wei" last="Tseng">Chih-Wei Tseng</name><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation></author><author><name sortKey="Lin, Ching Heng" sort="Lin, Ching Heng" uniqKey="Lin C" first="Ching-Heng" last="Lin">Ching-Heng Lin</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0731</institution-id><institution-id institution-id-type="GRID">grid.410764.0</institution-id><institution>Department of Medical Research,</institution><institution>Taichung Veterans General Hospital,</institution></institution-wrap>Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taichung</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff12"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0573 0416</institution-id><institution-id institution-id-type="GRID">grid.412146.4</institution-id><institution>Department of Healthcare Management,</institution><institution>National Taipei University of Nursing and Health Sciences,</institution></institution-wrap>Taipei, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Taipei</wicri:regionArea></affiliation></author></analytic><series><title level="j">Arthritis Research & Therapy</title><idno type="ISSN">1478-6354</idno><idno type="eISSN">1478-6362</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p id="Par1">To investigate the risk of immune-mediated inflammatory diseases (IMIDs) in patients with ankylosing spondylitis (AS).</p></sec><sec><title>Methods</title><p id="Par2">Using 2003–2012 claims data from the Taiwanese National Health Insurance Research Database, we identified 30,911 newly diagnosed AS patients requiring medical therapy from 2006 to 2012. In addition, we randomly selected 309,110 non-AS individuals matching (1:10) the AS patients with regard to age, sex and the year of the index date. After excluding subjects with the corresponding prior IMIDs, we calculated the incidence rates (IRs) of various IMIDs in the AS and non-AS cohorts and estimated the hazard ratios (HRs) with 95% confidence intervals after adjusting for age, sex, the Charlson comorbidity index, the frequency of ambulatory visits during the follow-up period and medications. We conducted sensitivity analyses by excluding those who developed IMIDs within 3 months after the index date.</p></sec><sec><title>Results</title><p id="Par3">In the follow-up period, we found that newly diagnosed AS patients had significantly increased risks of acute anterior uveitis, psoriasis, Sjögren’s syndrome, thromboangiitis obliterans, Behcet’s disease and sarcoidosis. However, the risk of Sjögren’s syndrome did not increase in AS patients in the sensitivity analysis. In the same period, this study found no significant differences in the risks of Crohn’s disease, ulcerative colitis, systemic lupus erythematosus, systemic sclerosis, dermatomyositis, polymyositis, pemphigus and vitiligo between newly diagnosed AS patients and non-AS individuals. AS patients had a significantly reduced risk of rheumatoid arthritis.</p></sec><sec><title>Conclusion</title><p id="Par4">Newly diagnosed Taiwanese AS patients had increased risks of acute anterior uveitis, psoriasis, thromboangiitis obliterans, Behcet’s disease and sarcoidosis, but a reduced risk of rheumatoid arthritis.</p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (10.1186/s13075-019-1980-1) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cooper, Gs" uniqKey="Cooper G">GS Cooper</name></author><author><name sortKey="Stroehla, Bc" uniqKey="Stroehla B">BC Stroehla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="El Gabalawy, H" uniqKey="El Gabalawy H">H El-Gabalawy</name></author><author><name sortKey="Guenther, Lc" uniqKey="Guenther L">LC Guenther</name></author><author><name sortKey="Bernstein, Cn" uniqKey="Bernstein C">CN Bernstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuek, A" uniqKey="Kuek A">A Kuek</name></author><author><name sortKey="Hazleman, Bl" uniqKey="Hazleman B">BL Hazleman</name></author><author><name sortKey="Ostor, Aj" uniqKey="Ostor A">AJ Ostor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="David, T" uniqKey="David T">T David</name></author><author><name sortKey="Ling, Sf" uniqKey="Ling S">SF Ling</name></author><author><name sortKey="Barton, A" uniqKey="Barton A">A Barton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Robinson, D" uniqKey="Robinson D">D Robinson</name></author><author><name sortKey="Hackett, M" uniqKey="Hackett M">M Hackett</name></author><author><name sortKey="Wong, J" uniqKey="Wong J">J Wong</name></author><author><name sortKey="Kimball, Ab" uniqKey="Kimball A">AB Kimball</name></author><author><name sortKey="Cohen, R" uniqKey="Cohen R">R Cohen</name></author><author><name sortKey="Bala, M" uniqKey="Bala M">M Bala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cohen, R" uniqKey="Cohen R">R Cohen</name></author><author><name sortKey="Robinson, D" uniqKey="Robinson D">D Robinson</name></author><author><name sortKey="Paramore, C" uniqKey="Paramore C">C Paramore</name></author><author><name sortKey="Fraeman, K" uniqKey="Fraeman K">K Fraeman</name></author><author><name sortKey="Renahan, K" uniqKey="Renahan K">K Renahan</name></author><author><name sortKey="Bala, M" uniqKey="Bala M">M Bala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brophy, S" uniqKey="Brophy S">S Brophy</name></author><author><name sortKey="Pavy, S" uniqKey="Pavy S">S Pavy</name></author><author><name sortKey="Lewis, P" uniqKey="Lewis P">P Lewis</name></author><author><name sortKey="Taylor, G" uniqKey="Taylor G">G Taylor</name></author><author><name sortKey="Bradbury, L" uniqKey="Bradbury L">L Bradbury</name></author><author><name sortKey="Robertson, D" uniqKey="Robertson D">D Robertson</name></author><author><name sortKey="Lovell, C" uniqKey="Lovell C">C Lovell</name></author><author><name sortKey="Calin, A" uniqKey="Calin A">A Calin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sieper, J" uniqKey="Sieper J">J Sieper</name></author><author><name sortKey="Poddubnyy, D" uniqKey="Poddubnyy D">D Poddubnyy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chou, Ct" uniqKey="Chou C">CT Chou</name></author><author><name sortKey="Pei, L" uniqKey="Pei L">L Pei</name></author><author><name sortKey="Chang, Dm" uniqKey="Chang D">DM Chang</name></author><author><name sortKey="Lee, Cf" uniqKey="Lee C">CF Lee</name></author><author><name sortKey="Schumacher, Hr" uniqKey="Schumacher H">HR Schumacher</name></author><author><name sortKey="Liang, Mh" uniqKey="Liang M">MH Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Hh" uniqKey="Chen H">HH Chen</name></author><author><name sortKey="Chen, Tj" uniqKey="Chen T">TJ Chen</name></author><author><name sortKey="Chen, Ym" uniqKey="Chen Y">YM Chen</name></author><author><name sortKey="Ying Ming, C" uniqKey="Ying Ming C">C Ying-Ming</name></author><author><name sortKey="Chen, Dy" uniqKey="Chen D">DY Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stolwijk, C" uniqKey="Stolwijk C">C Stolwijk</name></author><author><name sortKey="Van Tubergen, A" uniqKey="Van Tubergen A">A van Tubergen</name></author><author><name sortKey="Castillo Ortiz, Jd" uniqKey="Castillo Ortiz J">JD Castillo-Ortiz</name></author><author><name sortKey="Boonen, A" uniqKey="Boonen A">A Boonen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stolwijk, C" uniqKey="Stolwijk C">C Stolwijk</name></author><author><name sortKey="Essers, I" uniqKey="Essers I">I Essers</name></author><author><name sortKey="Van Tubergen, A" uniqKey="Van Tubergen A">A van Tubergen</name></author><author><name sortKey="Boonen, A" uniqKey="Boonen A">A Boonen</name></author><author><name sortKey="Bazelier, Mt" uniqKey="Bazelier M">MT Bazelier</name></author><author><name sortKey="De Bruin, Ml" uniqKey="De Bruin M">ML De Bruin</name></author><author><name sortKey="De Vries, F" uniqKey="De Vries F">F de Vries</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ho, Hh" uniqKey="Ho H">HH Ho</name></author><author><name sortKey="Chen, Jy" uniqKey="Chen J">JY Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, Tm" uniqKey="Cheng T">TM Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Linden, S" uniqKey="Van Der Linden S">S van der Linden</name></author><author><name sortKey="Valkenburg, Ha" uniqKey="Valkenburg H">HA Valkenburg</name></author><author><name sortKey="Cats, A" uniqKey="Cats A">A Cats</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sjolander, A" uniqKey="Sjolander A">A Sjolander</name></author><author><name sortKey="Greenland, S" uniqKey="Greenland S">S Greenland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deyo, Ra" uniqKey="Deyo R">RA Deyo</name></author><author><name sortKey="Cherkin, Dc" uniqKey="Cherkin D">DC Cherkin</name></author><author><name sortKey="Ciol, Ma" uniqKey="Ciol M">MA Ciol</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akaike, H" uniqKey="Akaike H">H Akaike</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Js" uniqKey="Lee J">JS Lee</name></author><author><name sortKey="Oh, Bl" uniqKey="Oh B">BL Oh</name></author><author><name sortKey="Lee, Hy" uniqKey="Lee H">HY Lee</name></author><author><name sortKey="Song, Yw" uniqKey="Song Y">YW Song</name></author><author><name sortKey="Lee, Ey" uniqKey="Lee E">EY Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bae, Jm" uniqKey="Bae J">JM Bae</name></author><author><name sortKey="Choo, Jy" uniqKey="Choo J">JY Choo</name></author><author><name sortKey="Kim, Kj" uniqKey="Kim K">KJ Kim</name></author><author><name sortKey="Park, Ks" uniqKey="Park K">KS Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yen, Hsu Heng" uniqKey="Yen H">Hsu-Heng Yen</name></author><author><name sortKey="Weng, Meng Tzu" uniqKey="Weng M">Meng-Tzu Weng</name></author><author><name sortKey="Tung, Chien Chih" uniqKey="Tung C">Chien-Chih Tung</name></author><author><name sortKey="Wang, Yu Ting" uniqKey="Wang Y">Yu-Ting Wang</name></author><author><name sortKey="Chang, Yuan Ting" uniqKey="Chang Y">Yuan Ting Chang</name></author><author><name sortKey="Chang, Chin Hao" uniqKey="Chang C">Chin-Hao Chang</name></author><author><name sortKey="Shieh, Ming Jium" uniqKey="Shieh M">Ming-Jium Shieh</name></author><author><name sortKey="Wong, Jau Min" uniqKey="Wong J">Jau-Min Wong</name></author><author><name sortKey="Wei, Shu Chen" uniqKey="Wei S">Shu-Chen Wei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eren, R" uniqKey="Eren R">R Eren</name></author><author><name sortKey="Can, M" uniqKey="Can M">M Can</name></author><author><name sortKey="Alibaz Oner, F" uniqKey="Alibaz Oner F">F Alibaz-Oner</name></author><author><name sortKey="Yilmaz Oner, S" uniqKey="Yilmaz Oner S">S Yilmaz-Oner</name></author><author><name sortKey="Yilmazer, B" uniqKey="Yilmazer B">B Yilmazer</name></author><author><name sortKey="Cefle, A" uniqKey="Cefle A">A Cefle</name></author><author><name sortKey="Direskeneli, H" uniqKey="Direskeneli H">H Direskeneli</name></author><author><name 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Chen</name><name sortKey="Chen, Hsin Hua" sort="Chen, Hsin Hua" uniqKey="Chen H" first="Hsin-Hua" last="Chen">Hsin-Hua Chen</name><name sortKey="Chen, Hsin Hua" sort="Chen, Hsin Hua" uniqKey="Chen H" first="Hsin-Hua" last="Chen">Hsin-Hua Chen</name><name sortKey="Chen, Hsin Hua" sort="Chen, Hsin Hua" uniqKey="Chen H" first="Hsin-Hua" last="Chen">Hsin-Hua Chen</name><name sortKey="Chen, Hsin Hua" sort="Chen, Hsin Hua" uniqKey="Chen H" first="Hsin-Hua" last="Chen">Hsin-Hua Chen</name><name sortKey="Chen, Yi Hsing" sort="Chen, Yi Hsing" uniqKey="Chen Y" first="Yi-Hsing" last="Chen">Yi-Hsing Chen</name><name sortKey="Chen, Yi Hsing" sort="Chen, Yi Hsing" uniqKey="Chen Y" first="Yi-Hsing" last="Chen">Yi-Hsing Chen</name><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><name sortKey="Chen, Yi Ming" sort="Chen, Yi Ming" uniqKey="Chen Y" first="Yi-Ming" last="Chen">Yi-Ming Chen</name><name sortKey="Hsieh, Tsu Yi" sort="Hsieh, Tsu Yi" uniqKey="Hsieh T" first="Tsu-Yi" last="Hsieh">Tsu-Yi Hsieh</name><name sortKey="Hsieh, Tsu Yi" sort="Hsieh, Tsu Yi" uniqKey="Hsieh T" first="Tsu-Yi" last="Hsieh">Tsu-Yi Hsieh</name><name sortKey="Hsieh, Tsu Yi" sort="Hsieh, Tsu Yi" uniqKey="Hsieh T" first="Tsu-Yi" last="Hsieh">Tsu-Yi Hsieh</name><name sortKey="Hsieh, Tsu Yi" sort="Hsieh, Tsu Yi" uniqKey="Hsieh T" first="Tsu-Yi" last="Hsieh">Tsu-Yi Hsieh</name><name sortKey="Hung, Wei Ting" sort="Hung, Wei Ting" uniqKey="Hung W" first="Wei-Ting" last="Hung">Wei-Ting Hung</name><name sortKey="Hung, Wei Ting" sort="Hung, Wei Ting" uniqKey="Hung W" first="Wei-Ting" last="Hung">Wei-Ting Hung</name><name sortKey="Lai, Kuo Lung" sort="Lai, Kuo Lung" uniqKey="Lai K" first="Kuo-Lung" last="Lai">Kuo-Lung Lai</name><name sortKey="Lai, Kuo Lung" sort="Lai, Kuo Lung" uniqKey="Lai K" first="Kuo-Lung" last="Lai">Kuo-Lung Lai</name><name sortKey="Lin, Ching Heng" sort="Lin, Ching Heng" uniqKey="Lin C" first="Ching-Heng" last="Lin">Ching-Heng Lin</name><name sortKey="Lin, Ching Heng" sort="Lin, Ching Heng" uniqKey="Lin C" first="Ching-Heng" last="Lin">Ching-Heng Lin</name><name sortKey="Lin, Ching Tsai" sort="Lin, Ching Tsai" uniqKey="Lin C" first="Ching-Tsai" last="Lin">Ching-Tsai Lin</name><name sortKey="Tseng, Chih Wei" sort="Tseng, Chih Wei" uniqKey="Tseng C" first="Chih-Wei" last="Tseng">Chih-Wei Tseng</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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